Ultrasonographic and Radiographic Evaluation of Zeolite/Collagen Nanocomposite Scaffolds Compared With Nanohydroxyapatite on Experimental Bone Defect Healing in Rabbit Femur

Objectives: The use of a biomaterial scaffold can improve the healing process bone defects. Using radiologic and ultrasonographic methods, this study aimed to evaluate effects zeolite/collagen nanocomposite nanohydroxyapatite (nHA) scaffolds on defect in rabbit femur. Materials Methods: Twenty-eight mature male New Zealand white rabbits were classified into four equal groups (n=7 each). In first group, was made, wound closed with no treatment; second nHA implanted defect; third implanted; fourth filled using autograft. Radiologic (Sedecal Veterinary X-Ray System, Model No. A6544-2) (Mindray Z5 Ultrasound Scanner) examinations done days 0, 15, 30, 45, 60 postoperatively. Results: There 0 7 any studied examination. highest lowest related treatment control group day after operation, respectively. angiogenesis levels treated 30 Also, filling higher than other groups. Conclusions: Zeolite/collagen bear crucial capability reconstruction defects be used fractures.